5FUR

Structure of human TFIID-IIA bound to core promoter DNA

Summary for 5FUR

• Entry DOI: 10.2210/pdb5fur/pdb
• EMDB information: 3305
• Descriptor: TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6, TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8, ... (11 entities in total)
• Functional Keywords: tfiid, tfiia, transcription, rna polymerase ii, general transcription factors, preinitiation complex, core promoter, dna binding
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus : P20226 P49848 Q7Z7C8 P52655 P52655 P52657 P21675 Q15545 Q6P1X5
• Total number of polymer chains: 12
• Total formula weight: 688289.19

Authors

Louder, R.K.,He, Y.,Lopez-Blanco, J.R.,Fang, J.,Chacon, P.,Nogales, E. (deposition date: 2016-01-29, release date: 2016-04-06, Last modification date: 2017-08-02)

• Primary citation: Louder, R.K.,He, Y.,Lopez-Blanco, J.R.,Fang, J.,Chacon, P.,Nogales, E.; Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.; Nature, 531:604-, 2016; PubMed: 27007846; DOI: 10.1038/NATURE17394

Experimental method

ELECTRON MICROSCOPY (8.5 Å)