5FQL

Insights into Hunter syndrome from the structure of iduronate-2- sulfatase

5FQL の概要

• エントリーDOI: 10.2210/pdb5fql/pdb
• 分子名称: IDURONATE-2-SULFATASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hydrolase, hunter syndrome
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62584.76

構造登録者

Demydchuk, M.,Hill, C.H.,Zhou, A.,Bunkoczi, G.,Stein, P.E.,Marchesan, D.,Deane, J.E.,Read, R.J. (登録日: 2015-12-11, 公開日: 2017-01-18, 最終更新日: 2020-07-29)

• 主引用文献: Demydchuk, M.,Hill, C.H.,Zhou, A.,Bunkoczi, G.,Stein, P.E.,Marchesan, D.,Deane, J.E.,Read, R.J.; Insights into Hunter syndrome from the structure of iduronate-2-sulfatase.; Nat Commun, 8:15786-15786, 2017; PubMed: 28593992; DOI: 10.1038/ncomms15786

実験手法

X-RAY DIFFRACTION (2.3 Å)