5FQD

Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase

Summary for 5FQD

Entry DOI	10.2210/pdb5fqd/pdb
Descriptor	DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, CASEIN KINASE I ISOFORM ALPHA, ... (6 entities in total)
Functional Keywords	ligase, dna binding
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	6
Total formula weight	368753.44
Authors	Petzold, G.,Fischer, E.S.,Thoma, N.H. (deposition date: 2015-12-09, release date: 2016-02-24, Last modification date: 2024-01-10)
Primary citation	Petzold, G.,Fischer, E.S.,Thoma, N.H. Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase. Nature, 532:127-, 2016 Cited by PubMed: 26909574 DOI: 10.1038/NATURE16979 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation