5FND
Dynamic Undocking and the Quasi-Bound State as tools for Drug Design
Summary for 5FND
Entry DOI | 10.2210/pdb5fnd/pdb |
Related | 5FNC 5FNF |
Descriptor | HEAT SHOCK PROTEIN, HSP90-ALPHA, N-(2-AZANYL-6-METHYL-1,3-BENZOTHIAZOL-5-YL)ETHANAMIDE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hsp90, drug design, chaperone, oncology |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 27015.18 |
Authors | Ruiz-Carmona, S.,Schmidtke, P.,Luque, F.J.,Baker, L.M.,Matassova, N.,Davis, B.,Roughley, S.,Murray, J.,Hubbard, R.,Barril, X. (deposition date: 2015-11-13, release date: 2016-11-23, Last modification date: 2024-01-10) |
Primary citation | Ruiz-Carmona, S.,Schmidtke, P.,Luque, F.J.,Baker, L.,Matassova, N.,Davis, B.,Roughley, S.,Murray, J.,Hubbard, R.,Barril, X. Dynamic undocking and the quasi-bound state as tools for drug discovery. Nat Chem, 9:201-206, 2017 Cited by PubMed: 28221352DOI: 10.1038/nchem.2660 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)