5FMK
Bcl-xL with Bak BH3 complex
Summary for 5FMK
Entry DOI | 10.2210/pdb5fmk/pdb |
Related | 5FMI 5FMJ |
Descriptor | BCL-XL, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, GLYCEROL, ... (4 entities in total) |
Functional Keywords | bcl-xl, bak, bh3 domain, apoptosis, bcl-2 family |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Mitochondrion membrane ; Single-pass membrane protein : Q16611 |
Total number of polymer chains | 2 |
Total formula weight | 22143.65 |
Authors | Fairlie, W.D.,Lee, E.F.,Smith, B.J.,Czabotar, P.E.,Colman, P.M. (deposition date: 2015-11-06, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Lee, E.F.,Grabow, S.,Chappaz, S.,Dewson, G.,Hockings, C.,Kluck, R.M.,Gray, D.H.,Witkowski, M.T.,Evangelista, M.,Pettikiriarachchi, A.,Bouillet, P.,Lane, R.M.,Czabotar, P.E.,Colman, P.M.,Smith, B.J.,Kile, B.T.,Fairlie, W.D. Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival. Genes Dev., 30:1240-, 2016 Cited by PubMed: 27198225DOI: 10.1101/GAD.279414.116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.731 Å) |
Structure validation
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