5FLV
Crystal structure of NKX2-5 and TBX5 bound to the Nppa promoter region
Summary for 5FLV
Entry DOI | 10.2210/pdb5flv/pdb |
Related | 5FM6 5FM7 |
Descriptor | HOMEOBOX PROTEIN NKX-2.5, T-BOX TRANSCRIPTION FACTOR TBX5, 5'-D(*TP*CP*TP*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP *TP*GP*AP*AP*GP*TP*GP*G)-3', 5'-D(*AP*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP *GP*TP*GP*AP*GP*AP*AP*G)-3', ... (4 entities in total) |
Functional Keywords | transcription |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Cellular location | Nucleus : P42582 |
Total number of polymer chains | 12 |
Total formula weight | 186190.66 |
Authors | Stirnimann, C.U.,Glatt, S.,Mueller, C.W. (deposition date: 2015-10-28, release date: 2016-02-10, Last modification date: 2024-01-10) |
Primary citation | Luna-Zurita, L.,Stirnimann, C.U.,Glatt, S.,Kaynak, B.L.,Thomas, S.,Baudin, F.,Samee, M.A.H.,He, D.,Small, E.M.,Mileikovsky, M.,Nagy, A.,Holloway, A.K.,Pollard, K.S.,Muller, C.W.,Bruneau, B.G. Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell(Cambridge,Mass.), 164:999-, 2016 Cited by PubMed: 26875865DOI: 10.1016/J.CELL.2016.01.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.005 Å) |
Structure validation
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