5FG4

Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe

5FG4 の概要

• エントリーDOI: 10.2210/pdb5fg4/pdb
• 分子名称: Peregrin, 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide (3 entities in total)
• 機能のキーワード: peregrin, moz-morf complex, transcription
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : P55201
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14144.01

構造登録者

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (登録日: 2015-12-20, 公開日: 2016-01-13, 最終更新日: 2024-01-10)

• 主引用文献: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe; To Be Published,

実験手法

X-RAY DIFFRACTION (1.65 Å)