5FFW

Crystal structure of the bromodomain of human BRPF1 in complex with H4K5acK8ac histone peptide

Summary for 5FFW

DescriptorPeregrin, Histone H4 (3 entities in total)
Functional Keywordsperegrin, moz-morf complex, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  P55201 Q0VAS5
Total number of polymer chains3
Total molecular weight28408.52
Authors
Primary citation
Tallant, C.,Nunez-Alonso, G.,Savitsky, P.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.
Crystal structure of the bromodomain of human BRPF1 in complex with H4K5acK8ac histone peptide
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.252500.5%10.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution