5FCB
Murine SMPDL3A in complex with AMP
Summary for 5FCB
Entry DOI | 10.2210/pdb5fcb/pdb |
Related | 5FC1 5FC5 5FC6 5FC7 5FCA |
Descriptor | Acid sphingomyelinase-like phosphodiesterase 3a, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | smpdl3a, sphingomyelin, nucleotide, amp, hydrolase |
Biological source | Mus musculus (Mouse) |
Cellular location | Secreted : P70158 |
Total number of polymer chains | 1 |
Total formula weight | 52815.49 |
Authors | Gorelik, A.,Illes, K.,Superti-Furga, G.,Nagar, B. (deposition date: 2015-12-15, release date: 2016-01-27, Last modification date: 2020-07-29) |
Primary citation | Gorelik, A.,Illes, K.,Superti-Furga, G.,Nagar, B. Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. J.Biol.Chem., 291:6376-6385, 2016 Cited by PubMed: 26792860DOI: 10.1074/jbc.M115.711085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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