5FAQ

OXA-48 in complex with FPI-1465

Summary for 5FAQ

• Entry DOI: 10.2210/pdb5faq/pdb
• Related: 5FA7 5FAO 5FAP 5FAS 5FAT
• Descriptor: Beta-lactamase, CADMIUM ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 57282.32

Authors

King, A.M.,King, D.T.,French, S.,Brouillette, E.,Asli, A.,Alexander, A.N.,Vuckovic, M.,Maiti, S.N.,Parr, T.R.,Brown, E.D.,Malouin, F.,Strynadka, N.C.J.,Wright, G.D. (deposition date: 2015-12-11, release date: 2016-01-20, Last modification date: 2023-09-27)

• Primary citation: King, A.M.,King, D.T.,French, S.,Brouillette, E.,Asli, A.,Alexander, J.A.,Vuckovic, M.,Maiti, S.N.,Parr, T.R.,Brown, E.D.,Malouin, F.,Strynadka, N.C.,Wright, G.D.; Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins.; Acs Chem.Biol., 11:864-868, 2016; PubMed: 26731698; DOI: 10.1021/acschembio.5b00944

Experimental method

X-RAY DIFFRACTION (1.96 Å)