5F8P

A Novel Inhibitor of the Obesity-Related Protein FTO

Summary for 5F8P

• Entry DOI: 10.2210/pdb5f8p/pdb
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase FTO, SULFATE ION, 4-chloranyl-6-[(2~{S})-6-chloranyl-2,4,4-trimethyl-7-oxidanyl-3~{H}-chromen-2-yl]benzene-1,3-diol, ... (6 entities in total)
• Functional Keywords: fat mass and obesity associated(fto) protein, small molecule, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9C0B1
• Total number of polymer chains: 1
• Total formula weight: 55489.06

Authors

Chai, J.,Zhou, B.,Liu, W.,Han, Z. (deposition date: 2015-12-09, release date: 2016-12-14)

• Primary citation: Chai, J.,Zhou, B.,Liu, W.,Han, Z.; Crystal structure of FTO-CHTB; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)