5F8P
A Novel Inhibitor of the Obesity-Related Protein FTO
Summary for 5F8P
Entry DOI | 10.2210/pdb5f8p/pdb |
Descriptor | Alpha-ketoglutarate-dependent dioxygenase FTO, SULFATE ION, 4-chloranyl-6-[(2~{S})-6-chloranyl-2,4,4-trimethyl-7-oxidanyl-3~{H}-chromen-2-yl]benzene-1,3-diol, ... (6 entities in total) |
Functional Keywords | fat mass and obesity associated(fto) protein, small molecule, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9C0B1 |
Total number of polymer chains | 1 |
Total formula weight | 55489.06 |
Authors | |
Primary citation | Chai, J.,Zhou, B.,Liu, W.,Han, Z. Crystal structure of FTO-CHTB To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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