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5F8P

A Novel Inhibitor of the Obesity-Related Protein FTO

Summary for 5F8P
Entry DOI10.2210/pdb5f8p/pdb
DescriptorAlpha-ketoglutarate-dependent dioxygenase FTO, SULFATE ION, 4-chloranyl-6-[(2~{S})-6-chloranyl-2,4,4-trimethyl-7-oxidanyl-3~{H}-chromen-2-yl]benzene-1,3-diol, ... (6 entities in total)
Functional Keywordsfat mass and obesity associated(fto) protein, small molecule, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q9C0B1
Total number of polymer chains1
Total formula weight55489.06
Authors
Chai, J.,Zhou, B.,Liu, W.,Han, Z. (deposition date: 2015-12-09, release date: 2016-12-14, Last modification date: 2024-11-06)
Primary citationChai, J.,Zhou, B.,Liu, W.,Han, Z.
Crystal structure of FTO-CHTB
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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PDB entries from 2024-11-13

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