5F8H

Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form)

Summary for 5F8H

Related5F8G 5F8I 5F8J 5F8L 5F8M 5F8N 5F8O
DescriptorGenome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... (7 entities in total)
Functional Keywordspolymerase-rna complex, elongation, nucleotide addition cycle, transferase-rna complex, transferase/rna
Biological sourceEnterovirus A71
More
Cellular locationHost cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Virion  E5RPG2
Total number of polymer chains3
Total molecular weight70028.08
Authors
Shu, B.,Gong, P. (deposition date: 2015-12-09, release date: 2016-06-22, Last modification date: 2016-08-03)
Primary citation
Shu, B.,Gong, P.
Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113:E4005-E4014, 2016
PubMed: 27339134 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1602591113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.244603.5%3.7%0.62MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution