5F6K
Crystal structure of the MLL3-Ash2L-RbBP5 complex
Summary for 5F6K
Entry DOI | 10.2210/pdb5f6k/pdb |
Related | 5F59 5F5E 5F5L |
Descriptor | Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... (7 entities in total) |
Functional Keywords | histone methylation, histone methyltransferase, mll-family proteins, set domain, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UBL3 Q8NEZ4 Q15291 |
Total number of polymer chains | 7 |
Total formula weight | 86552.41 |
Authors | |
Primary citation | Li, Y.,Han, J.,Zhang, Y.,Cao, F.,Liu, Z.,Li, S.,Wu, J.,Hu, C.,Wang, Y.,Shuai, J.,Chen, J.,Cao, L.,Li, D.,Shi, P.,Tian, C.,Zhang, J.,Dou, Y.,Li, G.,Chen, Y.,Lei, M. Structural basis for activity regulation of MLL family methyltransferases. Nature, 530:447-452, 2016 Cited by PubMed: 26886794DOI: 10.1038/nature16952 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.411 Å) |
Structure validation
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