Crystal structure of the alpha subunit of glycyl tRNA synthetase (GlyRS) from Aquifex aeolicus in complex with an analog of glycyl adenylate (Gly-SA)

Summary for 5F5W

DescriptorGlycine--tRNA ligase alpha subunit, 5'-O-(glycylsulfamoyl)adenosine (3 entities in total)
Functional Keywordsclass ii trna synthetase, ligase
Biological sourceAquifex aeolicus (strain VF5)
Cellular locationCytoplasm  O67081
Total number of polymer chains5
Total molecular weight179757.81
Valencia-Sanchez, M.I.,Torres-Larios, A. (deposition date: 2015-12-04, release date: 2016-05-11, Last modification date: 2016-07-27)
Primary citation
Valencia-Sanchez, M.I.,Rodriguez-Hernandez, A.,Ferreira, R.,Santamaria-Suarez, H.A.,Arciniega, M.,Dock-Bregeon, A.C.,Moras, D.,Beinsteiner, B.,Mertens, H.,Svergun, D.,Brieba, L.G.,Grtli, M.,Torres-Larios, A.
Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases.
J.Biol.Chem., 291:14430-14446, 2016
PubMed: 27226617 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M116.730382
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250303.1%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5f5w
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Molmil generated image of 5f5w
rotated about x axis by 90°
Molmil generated image of 5f5w
rotated about y axis by 90°