5F2U
Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D
Summary for 5F2U
| Entry DOI | 10.2210/pdb5f2u/pdb |
| Descriptor | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, s-farnesyl-l-cysteine methyl ester, FARNESYL, ... (4 entities in total) |
| Functional Keywords | lipid binding protein, immunoglobulin-like, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Cytoplasm, cytosol : O43924 |
| Total number of polymer chains | 4 |
| Total formula weight | 36079.52 |
| Authors | Fansa, E.K.,Isamil, S.,Wittinghofer, A. (deposition date: 2015-12-02, release date: 2016-04-13, Last modification date: 2024-01-10) |
| Primary citation | Fansa, E.K.,Koesling, S.K.,Zent, E.,Wittinghofer, A.,Ismail, S. PDE6delta-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity. Nat Commun, 7:11366-, 2016 Cited by PubMed: 27063844DOI: 10.1038/NCOMMS11366 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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