5F2U
Structure of Fully modified farnesylated INPP5E Peptide in complex with PDE6D
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005095 | molecular_function | GTPase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005929 | cellular_component | cilium |
| A | 0007601 | biological_process | visual perception |
| A | 0016020 | cellular_component | membrane |
| A | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| A | 0031267 | molecular_function | small GTPase binding |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0042995 | cellular_component | cell projection |
| A | 0050953 | biological_process | sensory perception of light stimulus |
| B | 0005095 | molecular_function | GTPase inhibitor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005929 | cellular_component | cilium |
| B | 0007601 | biological_process | visual perception |
| B | 0016020 | cellular_component | membrane |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0031267 | molecular_function | small GTPase binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0042995 | cellular_component | cell projection |
| B | 0050953 | biological_process | sensory perception of light stimulus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide CMT C 701 and ILE C 643 |
| Chain | Residue |
| A | ILE53 |
| A | LEU54 |
| A | CYS56 |
| A | VAL80 |
| A | ALA111 |
| A | TYR149 |
| C | SER641 |
| C | THR642 |
| C | FAR701 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residues CMT C 701 and FAR C 702 |
| Chain | Residue |
| A | ILE53 |
| A | CYS56 |
| A | GLN78 |
| A | ALA111 |
| A | THR131 |
| A | TYR149 |
| C | SER641 |
| C | ILE643 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residues CMT D 701 and FAR D 702 |
| Chain | Residue |
| B | ILE53 |
| B | CYS56 |
| B | VAL59 |
| B | GLN78 |
| B | THR131 |
| D | SER641 |
| D | ILE643 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide CMT D 701 and ILE D 643 |
| Chain | Residue |
| B | ILE53 |
| B | LEU54 |
| B | CYS56 |
| B | VAL59 |
| B | TYR149 |
| D | SER641 |
| D | THR642 |
| D | FAR701 |
