5F21

human CD38 in complex with nanobody MU375

Summary for 5F21

• Entry DOI: 10.2210/pdb5f21/pdb
• Related: 5F1K 5F1O
• Descriptor: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, nanobody MU375, SULFATE ION, ... (5 entities in total)
• Functional Keywords: cd38, adp-ribosyl cyclase, cyclic adp-ribose, x-crystallography, calcium signaling, nanobody, mu375, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type II membrane protein: P28907
• Total number of polymer chains: 2
• Total formula weight: 46418.03

Authors

Hao, Q.,Zhang, H. (deposition date: 2015-12-01, release date: 2016-06-15, Last modification date: 2023-11-08)

• Primary citation: Li, T.,Qi, S.,Unger, M.,Hou, Y.N.,Deng, Q.W.,Liu, J.,Lam, C.M.,Wang, X.W.,Xin, D.,Zhang, P.,Koch-Nolte, F.,Hao, Q.,Zhang, H.,Lee, H.C.,Zhao, Y.J.; Immuno-targeting the multifunctional CD38 using nanobody; Sci Rep, 6:27055-27055, 2016; PubMed: 27251573; DOI: 10.1038/srep27055

Experimental method

X-RAY DIFFRACTION (1.9 Å)