5F21
human CD38 in complex with nanobody MU375
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | polymer | 255 | 29536.5 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (Human) | CD38 |
| 2 | B (B) | nanobody MU375 | polymer | 156 | 16597.4 | 1 | Lama glama | ||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 46 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Thr 49 | Gln 49 | engineered mutation |
| Asp 100 | Asn 100 | engineered mutation |
| Asp 164 | Asn 164 | engineered mutation |
| Asp 209 | Asn 209 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46133.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 284.2 | |
| All* | Total formula weight | 46418.0 |
