5EX4

3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with tryptophan in all three allosteric binding sites

Summary for 5EX4

• Entry DOI: 10.2210/pdb5ex4/pdb
• Related: 2YPO 2YPP 2YPQ 3KGF 3NUE 3RZI 5E2L 5E40 5E4N 5E5G 5E7Z
• Descriptor: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, MANGANESE (II) ION, TRYPTOPHAN, ... (8 entities in total)
• Functional Keywords: transferase, shikimate pathway, allosteric regulation
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 103665.78

Authors

Reichau, S.,Jiao, W.,Blackmore, N.J.,Hutton, R.D.,Parker, E.J. (deposition date: 2015-11-23, release date: 2015-12-02, Last modification date: 2023-09-27)

• Primary citation: Reichau, S.,Blackmore, N.J.,Jiao, W.,Parker, E.J.; 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with tryptophan in all three allosteric binding sites; to be published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)