5EX4
3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with tryptophan in all three allosteric binding sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase | polymer | 464 | 50828.4 | 2 | UniProt (A0A0E8NFD1) Pfam (PF01474) UniProt (by SIFTS) (O53512) | Mycobacterium tuberculosis | |
| 2 | C, K (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, F, L, M, Q (A, B) | TRYPTOPHAN | non-polymer | 204.2 | 5 | Chemie (TRP) | |||
| 4 | E, J (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | G, I, N, O, S (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | H, P (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 7 | R (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | T, U (A, B) | water | water | 18.0 | 707 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 462 (UniProt: A0A0E8NFD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101656.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2009.0 | |
| All* | Total formula weight | 103665.8 |
