5ETC
Structure of inactive MAPK14 with ordered Activation Loop
Summary for 5ETC
Entry DOI | 10.2210/pdb5etc/pdb |
Descriptor | Mitogen-activated protein kinase 14, SULFATE ION (3 entities in total) |
Functional Keywords | mapk14, inactive kinase, activation loop, mapk, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 41812.73 |
Authors | Kapp, U.,Pellegrini, E.,Bowler, M.W. (deposition date: 2015-11-17, release date: 2016-01-20, Last modification date: 2023-09-27) |
Primary citation | Juyoux, P.,Galdadas, I.,Gobbo, D.,von Velsen, J.,Pelosse, M.,Tully, M.,Vadas, O.,Gervasio, F.L.,Pellegrini, E.,Bowler, M.W. Architecture of the MKK6-p38 alpha complex defines the basis of MAPK specificity and activation. Science, 381:1217-1225, 2023 Cited by PubMed: 37708276DOI: 10.1126/science.add7859 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.422 Å) |
Structure validation
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