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5ETC

Structure of inactive MAPK14 with ordered Activation Loop

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 14polymer36341716.71UniProt (Q16539)
Pfam (PF00069)
Homo sapiens (Human)MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C
(A)
waterwater18.0192Chemie (HOH)
Sequence modifications
A: 1 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Met -2-initiating methionine
Leu -1-expression tag
Glu 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41716.7
Non-Polymers*Number of molecules1
Total formula weight96.1
All*Total formula weight41812.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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