5EP3
Quorum-Sensing Signal Integrator LuxO - Catalytic Domain Bound to CV-133 Inhibitor
Summary for 5EP3
Entry DOI | 10.2210/pdb5ep3/pdb |
Related | 5EP0 5EP1 5EP2 5EP4 |
Descriptor | Putative repressor protein luxO, 2,2-dimethylpropyl 2-[(3-oxidanylidene-5-sulfanylidene-2~{H}-1,2,4-triazin-6-yl)amino]ethanoate, SULFATE ION, ... (6 entities in total) |
Functional Keywords | quorum sensing, aaa+ protein, catalytic domain, atpase, inhibitor, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Photobacterium angustum |
Total number of polymer chains | 1 |
Total formula weight | 29281.42 |
Authors | Shah, T.,Selcuk, H.B.,Jeffrey, P.D.,Hughson, F.M. (deposition date: 2015-11-11, release date: 2016-04-20, Last modification date: 2024-03-06) |
Primary citation | Boyaci, H.,Shah, T.,Hurley, A.,Kokona, B.,Li, Z.,Ventocilla, C.,Jeffrey, P.D.,Semmelhack, M.F.,Fairman, R.,Bassler, B.L.,Hughson, F.M. Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14:e1002464-e1002464, 2016 Cited by PubMed: 27219477DOI: 10.1371/journal.pbio.1002464 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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