5EP3
Quorum-Sensing Signal Integrator LuxO - Catalytic Domain Bound to CV-133 Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Putative repressor protein luxO | polymer | 256 | 28612.7 | 1 | UniProt (Q1ZS18) Pfam (PF00158) | Photobacterium angustum | |
| 2 | B (A) | 2,2-dimethylpropyl 2-[(3-oxidanylidene-5-sulfanylidene-2~{H}-1,2,4-triazin-6-yl)amino]ethanoate | non-polymer | 272.3 | 1 | Chemie (5QT) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | F (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 141 - 387 (UniProt: Q1ZS18)
| PDB | External Database | Details |
|---|---|---|
| Met 140 | - | initiating methionine |
| Leu 388 | - | expression tag |
| Glu 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| His 395 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28612.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 668.8 | |
| All* | Total formula weight | 29281.4 |
