5EP3

Quorum-Sensing Signal Integrator LuxO - Catalytic Domain Bound to CV-133 Inhibitor

5EP3 の概要

• エントリーDOI: 10.2210/pdb5ep3/pdb
• 関連するPDBエントリー: 5EP0 5EP1 5EP2 5EP4
• 分子名称: Putative repressor protein luxO, 2,2-dimethylpropyl 2-[(3-oxidanylidene-5-sulfanylidene-2~{H}-1,2,4-triazin-6-yl)amino]ethanoate, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: quorum sensing, aaa+ protein, catalytic domain, atpase, inhibitor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• 由来する生物種: Photobacterium angustum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29281.42

構造登録者

Shah, T.,Selcuk, H.B.,Jeffrey, P.D.,Hughson, F.M. (登録日: 2015-11-11, 公開日: 2016-04-20, 最終更新日: 2024-03-06)

• 主引用文献: Boyaci, H.,Shah, T.,Hurley, A.,Kokona, B.,Li, Z.,Ventocilla, C.,Jeffrey, P.D.,Semmelhack, M.F.,Fairman, R.,Bassler, B.L.,Hughson, F.M.; Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.; Plos Biol., 14:e1002464-e1002464, 2016; PubMed: 27219477; DOI: 10.1371/journal.pbio.1002464

実験手法

X-RAY DIFFRACTION (1.8 Å)