5EOZ
Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta
Summary for 5EOZ
Entry DOI | 10.2210/pdb5eoz/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (8 entities in total) |
Functional Keywords | human dna polymerase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48285.63 |
Authors | Koag, M.C.,Lee, S. (deposition date: 2015-11-10, release date: 2016-11-23, Last modification date: 2023-09-27) |
Primary citation | Kou, Y.,Koag, M.C.,Lee, S. Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018 Cited by PubMed: 29957995DOI: 10.1021/acs.biochem.8b00331 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.088 Å) |
Structure validation
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