5EMF
Crystal structure of RNA r(GCUGCUGC) with antisense PNA p(GCAGCAGC)
Summary for 5EMF
Entry DOI | 10.2210/pdb5emf/pdb |
Related | 5EME |
Descriptor | RNA (5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3'), antisense PNA p(GCAGCAGC), CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | cug repeats, rna/pna duplex, antisense pna, myotonic dystrophy type 1, rna |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 4793.58 |
Authors | Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. (deposition date: 2015-11-06, release date: 2016-01-13, Last modification date: 2023-11-15) |
Primary citation | Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs. Nucleic Acids Res., 44:1937-1943, 2016 Cited by PubMed: 26717983DOI: 10.1093/nar/gkv1513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.14 Å) |
Structure validation
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