5EKD

Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.

Summary for 5EKD

• Entry DOI: 10.2210/pdb5ekd/pdb
• Descriptor: Tryptophan--tRNA ligase, mitochondrial, (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: trprs, indolmycin, mitochondrial, complex, ligase-antibiotic complex, ligase/antibiotic
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 78020.80

Authors

Williams, T.L.,Carter Jr., C.W. (deposition date: 2015-11-03, release date: 2016-11-16, Last modification date: 2023-09-27)

• Primary citation: Williams, T.L.,Carter Jr., C.W.; Binding of Mg2+ATP Enhances Inhibition of Human Mitochondrial Tryptophanyl-tRNA Synthetase by Indolmycin; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.82 Å)