Crystal structure of the S-methyltransferase TmtA

Summary for 5EGP

DescriptorUbiE/COQ5 family methyltransferase, putative, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... (5 entities in total)
Functional Keywordsbis-thiomethyltransferase, gliotoxin, epipolythiodioxopiperazine, aspergillus fumigatus, transferase
Biological sourceAspergillus fumigatus Z5
Total number of polymer chains2
Total molecular weight72589.76
Duell, E.R.,Glaser, M.,Antes, I.,Groll, M.,Huber, E.M. (deposition date: 2015-10-27, release date: 2016-02-03, Last modification date: 2016-04-27)
Primary citation
Duell, E.R.,Glaser, M.,Le Chapelain, C.,Antes, I.,Groll, M.,Huber, E.M.
Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA.
Acs Chem.Biol., 11:1082-1089, 2016
PubMed: 26808594 (PDB entries with the same primary citation)
DOI: 10.1021/acschembio.5b00905
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16630 2.0% 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23