5E8E

Crystal structure of thrombin bound to an exosite 1-specific IgA Fab

Summary for 5E8E

• Entry DOI: 10.2210/pdb5e8e/pdb
• Related PRD ID: PRD_000020
• Descriptor: IGA FAB LIGHT CHAIN, SODIUM ION, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (12 entities in total)
• Functional Keywords: immune system-hydrolase complex, immune system, inhibitor, immune system/hydrolase
• Biological source: Homo sapiens (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 85481.57

Authors

Baglin, T.P.,Langdown, J.,Frasson, R.,Huntington, J.A. (deposition date: 2015-10-14, release date: 2015-10-28, Last modification date: 2024-01-10)

• Primary citation: Baglin, T.P.,Langdown, J.,Frasson, R.,Huntington, J.A.; Discovery and characterization of an antibody directed against exosite I of thrombin.; J.Thromb.Haemost., 14:137-142, 2016; PubMed: 26469093; DOI: 10.1111/jth.13171

Experimental method

X-RAY DIFFRACTION (1.9 Å)