5E51

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 1 with Faropenem adduct

Summary for 5E51

Entry DOI	10.2210/pdb5e51/pdb
Descriptor	L,D-transpeptidase 1, (3R)-3-hydroxybutanal (3 entities in total)
Functional Keywords	l, d-transpeptidase 1, peptidoglycan synthesis enzyme, cell wall enzyme, ldtmt1, mycobacterium tuberculosis, transferase
Biological source	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Cellular location	Periplasm : Q7DAG3
Total number of polymer chains	4
Total formula weight	96044.07
Authors	Kumar, P.,Lamichhane, G.,Ginell, S.L. (deposition date: 2015-10-07, release date: 2016-10-26, Last modification date: 2023-09-27)
Primary citation	Kumar, P.,Kaushik, A.,Lloyd, E.P.,Li, S.G.,Mattoo, R.,Ammerman, N.C.,Bell, D.T.,Perryman, A.L.,Zandi, T.A.,Ekins, S.,Ginell, S.L.,Townsend, C.A.,Freundlich, J.S.,Lamichhane, G. Non-classical transpeptidases yield insight into new antibacterials. Nat. Chem. Biol., 13:54-61, 2017 Cited by PubMed: 27820797 DOI: 10.1038/nchembio.2237 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation