5E2B

Crystal structure of NTMT1 in complex with N-terminally methylated PPKRIA peptide

Summary for 5E2B

• Entry DOI: 10.2210/pdb5e2b/pdb
• Related: 5E1B 5E1D 5E1M 5E1O 5E2A
• Descriptor: N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
• Functional Keywords: transferase, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q9BV86
• Total number of polymer chains: 4
• Total formula weight: 56986.92

Authors

Dong, C.,Tempel, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-09-30, release date: 2015-10-28, Last modification date: 2015-12-02)

• Primary citation: Dong, C.,Mao, Y.,Tempel, W.,Qin, S.,Li, L.,Loppnau, P.,Huang, R.,Min, J.; Structural basis for substrate recognition by the human N-terminal methyltransferase 1.; Genes Dev., 29:2343-2348, 2015; PubMed: 26543161; DOI: 10.1101/gad.270611.115

Experimental method

X-RAY DIFFRACTION (1.95 Å)