5DUO

Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group

5DUO の概要

• エントリーDOI: 10.2210/pdb5duo/pdb
• 関連するPDBエントリー: 4UC1
• 分子名称: Tryptophan-rich sensory protein, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, ... (5 entities in total)
• 機能のキーワード: mitochondria, transport, 5 transmembrane helices, membrane protein
• 由来する生物種: Rhodobacter sphaeroides
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 59834.77

構造登録者

Li, F.,Liu, J.,Zheng, Y.,Garavito, R.M.,Ferguson-Miller, S. (登録日: 2015-09-20, 公開日: 2015-11-11, 最終更新日: 2024-03-06)

主引用文献

Li, F.,Liu, J.,Zheng, Y.,Garavito, R.M.,Ferguson-Miller, S.
Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350:519-519, 2015

PubMed Abstract: Wang comments that the diffraction data for the structure of the A139T mutant of translocator protein TSPO from Rhodobacter sphaeroides should be used to 1.65 instead of 1.8 angstroms and that the density interpreted as porphyrin and monoolein is better fitted as polyethylene glycol. Although different practices of data processing exist, in this case they do not substantially influence the final map. Additional data are presented supporting the fit of a porphyrin and monooleins.

PubMed: 26516277
DOI: 10.1126/science.aab2595

実験手法

X-RAY DIFFRACTION (2.4 Å)