5DSE

Crystal Structure of the TTC7B/Hyccin Complex

Summary for 5DSE

• Entry DOI: 10.2210/pdb5dse/pdb
• Related: 4N5C
• Descriptor: Tetratricopeptide repeat protein 7B, Hyccin (3 entities in total)
• Functional Keywords: pi4p synthesis, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytosol : Q86TV6 Q9BYI3
• Total number of polymer chains: 4
• Total formula weight: 257160.85

Authors

Wu, X.,Baskin, J.M.,Reinisch, K.M.,De Camilli, P. (deposition date: 2015-09-17, release date: 2015-12-02, Last modification date: 2023-12-27)

• Primary citation: Baskin, J.M.,Wu, X.,Christiano, R.,Oh, M.S.,Schauder, C.M.,Gazzerro, E.,Messa, M.,Baldassari, S.,Assereto, S.,Biancheri, R.,Zara, F.,Minetti, C.,Raimondi, A.,Simons, M.,Walther, T.C.,Reinisch, K.M.,De Camilli, P.; The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.; Nat.Cell Biol., 18:132-138, 2016; PubMed: 26571211; DOI: 10.1038/ncb3271

Experimental method

X-RAY DIFFRACTION (2.9 Å)