5DS5
Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA and Mg
Summary for 5DS5
Entry DOI | 10.2210/pdb5ds5/pdb |
Related | 4P6I 5DS4 5DS6 |
Descriptor | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... (5 entities in total) |
Functional Keywords | adaptive immunity, crispr-associated proteins, crispr-cas systems, clustered regularly interspaced short palindromic repeats, integrases, endodeoxyribonucleases, endonucleases, dna binding protein, hydrolase-dna complex, hydrolase/dna |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 8 |
Total formula weight | 173995.57 |
Authors | Nunez, J.K.,Harrington, L.B.,Kranzusch, P.J.,Engelman, A.N.,Doudna, J.A. (deposition date: 2015-09-16, release date: 2015-10-28, Last modification date: 2023-09-27) |
Primary citation | Nunez, J.K.,Harrington, L.B.,Kranzusch, P.J.,Engelman, A.N.,Doudna, J.A. Foreign DNA capture during CRISPR-Cas adaptive immunity. Nature, 527:535-538, 2015 Cited by PubMed: 26503043DOI: 10.1038/nature15760 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.951 Å) |
Structure validation
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