5DNM
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
Summary for 5DNM
Entry DOI | 10.2210/pdb5dnm/pdb |
Related | 5DNN |
Descriptor | Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total) |
Functional Keywords | nucleosome, ruthenium antitumour compound, histone binding, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 199290.18 |
Authors | Adhireksan, Z.,Muhammad, R.,Davey, C.A. (deposition date: 2015-09-10, release date: 2016-09-14, Last modification date: 2023-11-08) |
Primary citation | Adhireksan, Z.,Palermo, G.,Riedel, T.,Ma, Z.,Muhammad, R.,Rothlisberger, U.,Dyson, P.J.,Davey, C.A. Allosteric cross-talk in chromatin can mediate drug-drug synergy Nat Commun, 8:14860-14860, 2017 Cited by PubMed: 28358030DOI: 10.1038/ncomms14860 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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