5DKD

Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe

5DKD の概要

• エントリーDOI: 10.2210/pdb5dkd/pdb
• 分子名称: Transcription activator BRG1, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: swi-snf complex, chromatin remodeling, brg associated factors (baf), transcription, hydrolase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : P51532
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29606.87

構造登録者

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (登録日: 2015-09-03, 公開日: 2015-10-14, 最終更新日: 2024-01-10)

• 主引用文献: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)