5DHG
The crystal structure of nociceptin/orphanin FQ peptide receptor (NOP) in complex with C-35 (PSI Community Target)
Summary for 5DHG
Entry DOI | 10.2210/pdb5dhg/pdb |
Related | 4EA3 |
Descriptor | Soluble cytochrome b562,Nociceptin receptor, 1-benzyl-N-{3-[4-(2,6-dichlorophenyl)piperidin-1-yl]propyl}-D-prolinamide, OLEIC ACID, ... (4 entities in total) |
Functional Keywords | nociceptin/orphanin fq peptide receptor, nop, orl-1, n/ofq, opioid receptor, g protein-coupled receptor, gpcr, membrane protein, lipidic cubic phase, bret, receptor-ligand conformational pair, structural genomics, psi-biology, gpcr network, signaling protein, psicnt-127 |
Biological source | Escherichia coli More |
Cellular location | Cell membrane; Multi-pass membrane protein: P41146 |
Total number of polymer chains | 2 |
Total formula weight | 96110.52 |
Authors | Miller, R.L.,Thompson, A.A.,Trapella, C.,Guerrini, R.,Malfacini, D.,Patel, N.,Han, G.W.,Cherezov, V.,Calo, G.,Katritch, V.,Stevens, R.C.,GPCR Network (GPCR) (deposition date: 2015-08-30, release date: 2015-10-21, Last modification date: 2023-09-27) |
Primary citation | Miller, R.L.,Thompson, A.A.,Trapella, C.,Guerrini, R.,Malfacini, D.,Patel, N.,Han, G.W.,Cherezov, V.,Calo, G.,Katritch, V.,Stevens, R.C. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure, 23:2291-2299, 2015 Cited by PubMed: 26526853DOI: 10.1016/j.str.2015.07.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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