5DBI

Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NAD+ and 10-oxogeranial

Summary for 5DBI

Entry DOI	10.2210/pdb5dbi/pdb
Related	5DBF 5DBG
Descriptor	Iridoid synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2E,6E)-2,6-dimethylocta-2,6-dienedial, ... (4 entities in total)
Functional Keywords	metal-binding, substrate binding, acidocalcisomal pyrophosphatase, inhibitor, oxidoreductase
Biological source	Catharanthus roseus (Madagascar periwinkle)
Cellular location	Cytoplasm, cytosol : K7WDL7
Total number of polymer chains	2
Total formula weight	86226.12
Authors	Hu, Y.M.,Liu, W.D.,Zheng, Y.Y.,Xu, Z.X.,Ko, T.P.,Chen, C.C.,Guo, R.T. (deposition date: 2015-08-21, release date: 2015-11-04, Last modification date: 2023-11-08)
Primary citation	Hu, Y.M.,Liu, W.D.,Malwal, S.R.,Zheng, Y.Y.,Feng, X.X.,Ko, T.P.,Chen, C.C.,Xu, Z.X.,Liu, M.X.,Han, X.,Gao, J.,Oldfield, E.,Guo, R.T. Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms Angew.Chem.Int.Ed.Engl., 54:15478-15482, 2015 Cited by PubMed: 26768532 DOI: 10.1002/anie.201508310 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation