5DBI
Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NAD+ and 10-oxogeranial
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006720 | biological_process | isoprenoid metabolic process |
| A | 0016099 | biological_process | monoterpenoid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006720 | biological_process | isoprenoid metabolic process |
| B | 0016099 | biological_process | monoterpenoid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | GLY36 |
| A | VAL107 |
| A | SER108 |
| A | TRP109 |
| A | MET121 |
| A | GLN142 |
| A | THR143 |
| A | TYR178 |
| A | PRO201 |
| A | ALA202 |
| A | VAL204 |
| A | THR38 |
| A | SER211 |
| A | MET212 |
| A | MET213 |
| A | XOG402 |
| A | HOH523 |
| A | HOH530 |
| A | HOH540 |
| A | HOH541 |
| A | HOH555 |
| A | GLY39 |
| A | ILE40 |
| A | ALA65 |
| A | ARG66 |
| A | CYS83 |
| A | ASP84 |
| A | VAL85 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue XOG A 402 |
| Chain | Residue |
| A | GLY144 |
| A | ILE145 |
| A | LYS146 |
| A | TYR178 |
| A | ILE345 |
| A | ALA346 |
| A | NAD401 |
| A | HOH561 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | binding site for residue NAD B 401 |
| Chain | Residue |
| B | GLY36 |
| B | THR38 |
| B | GLY39 |
| B | ILE40 |
| B | ALA65 |
| B | ARG66 |
| B | CYS83 |
| B | ASP84 |
| B | VAL85 |
| B | VAL107 |
| B | SER108 |
| B | TRP109 |
| B | MET121 |
| B | GLN142 |
| B | THR143 |
| B | TYR178 |
| B | PRO201 |
| B | ALA202 |
| B | VAL204 |
| B | SER211 |
| B | MET212 |
| B | MET213 |
| B | XOG402 |
| B | HOH519 |
| B | HOH531 |
| B | HOH536 |
| B | HOH542 |
| B | HOH544 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue XOG B 402 |
| Chain | Residue |
| B | GLY144 |
| B | ILE145 |
| B | LYS146 |
| B | TYR178 |
| B | ILE345 |
| B | NAD401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"26768532","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26551396","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26768532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26868105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5COB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DF1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26768532","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DBI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26768532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26868105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5COB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DBI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26768532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26868105","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5COB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
