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5D9Q

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46

5D9Q の概要
エントリーDOI10.2210/pdb5d9q/pdb
関連するPDBエントリー4NCO 4TVP 5KZC
分子名称Envelope glycoprotein gp120, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
機能のキーワードhiv env glycoprotein; broadly neutralizing antibodies; immune system, immune system
由来する生物種Human immunodeficiency virus 1
詳細
タンパク質・核酸の鎖数15
化学式量合計473368.32
構造登録者
Julien, J.-P.,Stanfield, R.L.,Ward, A.B.,Wilson, I.A. (登録日: 2015-08-18, 公開日: 2016-08-17, 最終更新日: 2023-09-27)
主引用文献Jardine, J.G.,Sok, D.,Julien, J.P.,Briney, B.,Sarkar, A.,Liang, C.H.,Scherer, E.A.,Henry Dunand, C.J.,Adachi, Y.,Diwanji, D.,Hsueh, J.,Jones, M.,Kalyuzhniy, O.,Kubitz, M.,Spencer, S.,Pauthner, M.,Saye-Francisco, K.L.,Sesterhenn, F.,Wilson, P.C.,Galloway, D.M.,Stanfield, R.L.,Wilson, I.A.,Burton, D.R.,Schief, W.R.
Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
Plos Pathog., 12:e1005815-e1005815, 2016
Cited by
PubMed: 27560183
DOI: 10.1371/journal.ppat.1005815
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (4.4 Å)
構造検証レポート
Validation report summary of 5d9q
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-07-24に公開中

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