5CU5

Crystal structure of ERAP2 without catalytic Zn(II) atom

5CU5 の概要

• エントリーDOI: 10.2210/pdb5cu5/pdb
• 分子名称: Endoplasmic reticulum aminopeptidase 2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: hydrolase, aminopeptidase, endoplasmic reticulum, thermolysin-like catalytic domain
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 227235.80

構造登録者

Saridakis, E.,Mathioudakis, N.,Giastas, P.,Mavridis, I.M.,Stratikos, E. (登録日: 2015-07-24, 公開日: 2015-09-23, 最終更新日: 2024-01-10)

• 主引用文献: Mpakali, A.,Giastas, P.,Mathioudakis, N.,Mavridis, I.M.,Saridakis, E.,Stratikos, E.; Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2.; J.Biol.Chem., 290:26021-26032, 2015; PubMed: 26381406; DOI: 10.1074/jbc.M115.685909

実験手法

X-RAY DIFFRACTION (3.02 Å)