5CQB

Crystal structure of E. coli undecaprenyl pyrophosphate synthase

Summary for 5CQB

Entry DOI	10.2210/pdb5cqb/pdb
Related	5CQJ
Descriptor	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), TRIETHYLENE GLYCOL (3 entities in total)
Functional Keywords	transferase, cell wall, wall teichoic acid, antibacterial
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	2
Total formula weight	56850.04
Authors	Worrall, L.J.,Conrady, D.G.,Strynadka, N.C. (deposition date: 2015-07-21, release date: 2015-08-19, Last modification date: 2024-03-06)
Primary citation	Farha, M.A.,Czarny, T.L.,Myers, C.L.,Worrall, L.J.,French, S.,Conrady, D.G.,Wang, Y.,Oldfield, E.,Strynadka, N.C.,Brown, E.D. Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proc.Natl.Acad.Sci.USA, 112:11048-11053, 2015 Cited by PubMed: 26283394 DOI: 10.1073/pnas.1511751112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation