5CLE
Alkylpurine DNA glycosylase AlkD bound to DNA containing an abasic-site analog and a free 3-methyladenine nucleobase
Summary for 5CLE
Entry DOI | 10.2210/pdb5cle/pdb |
Related | 5CL3 5CL4 5CL5 5CL6 5CL7 5CL8 5CL9 5CLA 5CLB 5CLC 5CLD |
Descriptor | AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(3DR)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*TP*TP*CP*GP*GP*G)-3'), ... (5 entities in total) |
Functional Keywords | dna glycosylase, heat-like repeat, protein-dna complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Bacillus cereus More |
Total number of polymer chains | 3 |
Total formula weight | 35920.87 |
Authors | Mullins, E.A.,Eichman, B.F. (deposition date: 2015-07-16, release date: 2015-10-28, Last modification date: 2023-09-27) |
Primary citation | Mullins, E.A.,Shi, R.,Parsons, Z.D.,Yuen, P.K.,David, S.S.,Igarashi, Y.,Eichman, B.F. The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527:254-258, 2015 Cited by PubMed: 26524531DOI: 10.1038/nature15728 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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