5CJ8

Human Osteoclast Associated Receptor (OSCAR) extracellular domain

Summary for 5CJ8

Related5CJB
DescriptorOsteoclast-associated immunoglobulin-like receptor (2 entities in total)
Functional Keywordsimmunoglobulin-like, monomer, immune system
Biological sourceHomo sapiens (Human)
Cellular locationIsoform 1: Secreted . Isoform 2: Cell membrane ; Single-pass type I membrane protein  Q8IYS5
Total number of polymer chains1
Total molecular weight20369.4
Authors
Gao, G.F.,Qi, J.,Shi, Y.,Haywood, J. (deposition date: 2015-07-14, release date: 2016-01-20, Last modification date: 2016-02-10)
Primary citation
Haywood, J.,Qi, J.,Chen, C.C.,Lu, G.,Liu, Y.,Yan, J.,Shi, Y.,Gao, G.F.
Structural basis of collagen recognition by human osteoclast-associated receptor and design of osteoclastogenesis inhibitors.
Proc.Natl.Acad.Sci.USA, 113:1038-1043, 2016
PubMed: 26744311 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1522572113
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.015 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.248802.7%1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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