5CIY
Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain
Summary for 5CIY
Entry DOI | 10.2210/pdb5ciy/pdb |
Descriptor | Modification methylase HhaI, DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), ... (6 entities in total) |
Functional Keywords | cg-specificity, cpg sequence, c5-methylcytosine, nucleotide flipping, s-adenosyl-l-homocysteine, complex (methyltransferase- dna), transferase-dna complex, transferase/dna |
Biological source | Haemophilus parahaemolyticus More |
Total number of polymer chains | 3 |
Total formula weight | 45412.82 |
Authors | Rondelet, G.,DAL MASO, T.,Willems, L.,Wouters, J. (deposition date: 2015-07-13, release date: 2016-03-30, Last modification date: 2024-01-10) |
Primary citation | Rondelet, G.,Dal Maso, T.,Willems, L.,Wouters, J. Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194:357-367, 2016 Cited by PubMed: 26993463DOI: 10.1016/j.jsb.2016.03.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.594 Å) |
Structure validation
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