5CC2

STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE IONOTROPIC GLUTAMATE RECEPTOR-LIKE GLUD2 IN COMPLEX WITH 7-CKA

Summary for 5CC2

• Entry DOI: 10.2210/pdb5cc2/pdb
• Related: 2V3T 2V3U
• Descriptor: Glutamate receptor ionotropic, delta-2, 7-Chlorokynurenic acid, GLYCEROL, ... (5 entities in total)
• Functional Keywords: ionotropic glutamate receptor, glud2, ligand binding domain, nmda receptor antagonist, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : Q63226
• Total number of polymer chains: 1
• Total formula weight: 30736.06

Authors

Naur, P.,Gajhede, M.,Kastrup, J.S. (deposition date: 2015-07-01, release date: 2015-12-30, Last modification date: 2024-01-10)

• Primary citation: Kristensen, A.S.,Hansen, K.B.,Naur, P.,Olsen, L.,Kurtkaya, N.L.,Dravid, S.M.,Kvist, T.,Yi, F.,Phlsgaard, J.,Clausen, R.P.,Gajhede, M.,Kastrup, J.S.,Traynelis, S.F.; Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors.; Mol.Pharmacol., 89:253-262, 2016; PubMed: 26661043; DOI: 10.1124/mol.115.100909

Experimental method

X-RAY DIFFRACTION (2.501 Å)