5CC2

STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE IONOTROPIC GLUTAMATE RECEPTOR-LIKE GLUD2 IN COMPLEX WITH 7-CKA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue CKA A 301

Chain	Residue
A	GLU12
A	ASP194
A	VAL197
A	TYR222
A	HOH403
A	PHE15
A	TYR58
A	ALA85
A	LEU86
A	THR87
A	ARG92
A	ALA138
A	TRP193

---

site_id	AC2
Number of Residues	7
Details	binding site for residue CKA A 302

Chain	Residue
A	VAL107
A	HIS142
A	VAL143
A	TYR157
A	MET160
A	ASN215
A	VAL217

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CKA A 303

Chain	Residue
A	VAL174
A	VAL174
A	ALA179
A	ALA179
A	GLN182
A	LYS183

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 304

Chain	Residue
A	LEU11
A	GLU12
A	HIS56
A	TYR58
A	HOH401
A	HOH405

---

site_id	AC5
Number of Residues	1
Details	binding site for residue CL A 305

Chain	Residue
A	TYR48

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O43424","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9ULK0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---