5CC1
S425G Glucocorticoid receptor DNA binding domain - (+)GRE complex
Summary for 5CC1
Entry DOI | 10.2210/pdb5cc1/pdb |
Descriptor | Glucocorticoid receptor, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), ... (5 entities in total) |
Functional Keywords | dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 73456.70 |
Authors | Hudson, W.H.,Weikum, E.A.,Ortlund, E.A. (deposition date: 2015-07-01, release date: 2015-12-23, Last modification date: 2024-03-06) |
Primary citation | Hudson, W.H.,Kossmann, B.R.,de Vera, I.M.,Chuo, S.W.,Weikum, E.R.,Eick, G.N.,Thornton, J.W.,Ivanov, I.N.,Kojetin, D.J.,Ortlund, E.A. Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. Proc.Natl.Acad.Sci.USA, 113:326-331, 2016 Cited by PubMed: 26715749DOI: 10.1073/pnas.1518960113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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