5C9V
Structure of human Parkin G319A
Summary for 5C9V
Entry DOI | 10.2210/pdb5c9v/pdb |
Descriptor | E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | parkin, ubiquitin, e3 ligase, rbr, parkinson's disease, mitophagy, cell signalling, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol : O60260 |
Total number of polymer chains | 1 |
Total formula weight | 38268.06 |
Authors | Wauer, T.,Komander, D. (deposition date: 2015-06-29, release date: 2015-07-22, Last modification date: 2024-01-10) |
Primary citation | Wauer, T.,Simicek, M.,Schubert, A.,Komander, D. Mechanism of phospho-ubiquitin-induced PARKIN activation. Nature, 524:370-374, 2015 Cited by PubMed: 26161729DOI: 10.1038/nature14879 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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